Food and nutritional education: benefits of flavonoid consumption by children with Diabetes Mellitus

Authors

DOI:

https://doi.org/10.14571/brajets.v18.n4.1375-1386

Keywords:

functional food, school feeding, nutrition, antioxidants, chronic disease

Abstract

Brazil is the third country among the five countries with the highest number of cases of type 1 diabetes mellitus (DM1) in children and adolescents. Although this subtype is more common in these stages of life, type 2 has been increasing due to overweight and obesity. Flavonoids, phenolic compounds widely present in the plant kingdom, have anti-hyperglycemic, antioxidant and anti-inflammatory actions. The National School Feeding Program offers specialized care for students with special dietary needs, with differentiated menus and actions of Food and Nutrition Education (FNE) aimed at promoting health. This study aimed to discuss the benefits of flavonoids for the care of DM1 in school-aged children and elucidate the importance of EAN to spread knowledge about these substances. An integrative literature review was carried out, with selected through the databases Scientific Electronic Library Online - SciELO, Public Medline - PubMed, cross references through these articles, documents from the Ministry of Education and the Ministry of Development and Social Assistance and Fight against Hunger, as well as data from the Brazilian Institute of Geography and Statistics, the American Diabetes Association and the Brazilian Society of Diabetes. Flavonoids can act on DM by several mechanisms, such as modulation of the insulin signaling pathway, inflammation inhibition, lipotoxicity and oxidative stress. Thus, the consumption of flavonoids should be encouraged and EAN actions are effective to raise awareness about their benefits.

Author Biographies

  • Neila Ingrid dos Prazeres Santos, Federal University of Recôncavo da Bahia
    Nutritionist (CRN-5 23957/P) and Bachelor of Health from the Federal University
    of Recôncavo da Bahia (UFRB), postgraduate student in sports nutrition.
    She was part of the Collaborating Center for School Food and Nutrition
    of the Federal University of Recôncavo da Bahia (CECANE - UFRB).
    Active as a scholarship holder linked to the extension project
    "Family Farming of Quilombola Communities: Promoting the meeting between
    demand and supply". She worked as an intern in Clinical Nutrition at the Regional
    Hospital of Santo Antônio de Jesus (HRSAJ). She participated in the extension project
    "Health Promotion in Santo Antônio de Jesus (PROSAJ)". She offered teaching monitoring
    in the curricular component "Special Topics in Clinical Nutrition I". She worked as
    an intern in the Food and Nutrition Unit (UAN) at the Federal Institute of Bahia (IFBA),
    Santo Antônio de Jesus campus. She worked as an intern in Nutrition in Public Health
    at the Federal Institute of Bahia (IFBA), Santo Antônio de Jesus campus.
  • Karina Zanoti Fonseca, Federal University of Recôncavo da Bahia

    Nutricionista, mestre em Ciências Farmacêuticas, doutora em Bioquímica Agrícola pela Universidade Federal de Viçosa. Professora Associada na Universidade Federal do Recôncavo da Bahia. Principais áreas: Flavonoides, Desenvolvimento de produtos, Inovação Tecnológica, Alimentação Coletiva e Ciência dos Alimentos. Principais linhas de pesquisa: Química de Produtos Naturais, Substâncias Bioativas em Alimentos, Desenvolvimento de Novos Produtos, Alimentação Coletiva e Gestão de Unidades de Alimentação e Nutrição

References

Al Duhaidahawi, D., Hasan, S. A., & Al Zubaidy, H. F. S. (2021). Flavonoids in the treatment of diabetes: Clinical outcomes and mechanism to ameliorate blood glucose levels. Current Diabetes Reviews, 17(6), 26–42.

Al-Ishaq, R. K., Abotaleb, M., Kubatka, P., Kajo, K., & Büsselberg, D. (2019). Flavonoids and their anti-diabetic effects: Cellular mechanisms and effects to improve blood sugar levels. Biomolecules, 9(9), 430.

American Diabetes Association. (2020). 13. Children and adolescents: Standards of medical care in diabetes − 2020. Diabetes Care, 43 (Supplement_1), S163-S182.

American Diabetes Association. (2021). Introduction: Standards of medical care in diabetes − 2022. Diabetes Care, 45 (Supplement_1), S1-S2.

Batista, T. M., Haider, N., & Kahn, C. R. (2021). Defining the underlying defect in insulin action in type 2 diabetes. Diabetologia, 64, 994-1006.

Brasil. Ministério da Educação. Fundo Nacional de Desenvolvimento da Educação. (2013). Resolução/CD/FNDE nº 26, de 17 de junho de 2013: Dispõe sobre o atendimento da alimentação escolar aos alunos da educação básica no Programa Nacional de Alimentação Escolar – PNAE. Diário Oficial da União.

Brasil. Ministério da Educação. Programa Nacional de Alimentação Escolar. (2017). Caderno de referência sobre alimentação escolar para estudantes com necessidades alimentares especiais (65 p.). FNDE.

Brasil. Ministério da Saúde. (2020). Resolução nº 6, de 8 de maio de 2020: Dispõe sobre o atendimento da alimentação escolar aos alunos da educação básica no âmbito do Programa Nacional de Alimentação Escolar – PNAE.

Brasil. Ministério do Desenvolvimento Social e Combate à Fome. (2012). Marco de referência de educação alimentar e nutricional para as políticas públicas. MDS.

Chiang, J. L., Kirkman, M. S., Laffel, L. M. B., & Peters, A. L. (2018). Type 1 diabetes in children and adolescents: A position statement by the American Diabetes Association. Diabetes Care, 41(9), 2026-2044.

Colares, S. S., et al. (2020). Gestão do cuidado de estudantes com necessidades alimentares especiais vinculados ao Programa Nacional de Alimentação Escolar. Physis: Revista de Saúde Coletiva, 30(4), e300407.

Cremonini, E., Fraga, C. G., & Oteiza, P. I. (2019). (–)-Epicatechin in the control of glucose homeostasis: Involvement of redox-regulated mechanisms. Free Radical Biology and Medicine, 130, 478-488.

Dias, M. C., Pinto, D. C. G. A., & Silva, A. M. S. (2021). Plant flavonoids: Chemical characteristics and biological activity. Molecules, 26(17), 5377.

Dinda, B., et al. (2020). Dietary plant flavonoids in prevention of obesity and diabetes. Advances in Protein Chemistry and Structural Biology, 120, 159–235.

Faria, C. C., et al. (2022). Elaboration and validation of an e-book with the laws about diabetes in schools. Revista Brasileira de Enfermagem, 75, e20200711.

Fonseca, K. Z., et al. (2023). Ação educativa sobre flavonoides na alimentação escolar: Relato de experiência. Revista Educação em Saúde/Revista Educação em Saúde Unievangélica, 11(1), 60-70.

Fonseca, K. Z., Belloli, O. B., Silva, L. C., & Cenci, A. (2023). O livro de receitas da merendeira (J. Pasini, Org.; J. A. P. Farias, Ilust.). IFRS. (55 p.)

Ginwala, R., et al. (2019). Potential role of flavonoids in treating chronic inflammatory diseases with a special focus on the anti-inflammatory activity of apigenin. Antioxidants, 8(2), 35.

Kawser Hossain, M., et al. (2016). Molecular mechanisms of the anti-obesity and anti-diabetic properties of flavonoids. International Journal of Molecular Sciences, 17(4), 569.

Hussain, T., et al. (2020). Flavonoids and type 2 diabetes: Evidence of efficacy in clinical and animal studies and delivery strategies to enhance their therapeutic efficacy. Pharmacological Research, 152, 104629.

Hussain, T., et al. (2016). Oxidative stress and inflammation: What polyphenols can do for us? Oxidative Medicine and Cellular Longevity, 2016, 7432797.

Jubaidi, F. F., et al. (2021). The potential role of flavonoids in ameliorating diabetic cardiomyopathy via alleviation of cardiac oxidative stress, inflammation and apoptosis. International Journal of Molecular Sciences, 22(10), 5094.

Magliano, D. J., et al. (2021). Global picture. In IDF Diabetes Atlas (10th ed.) [Internet]. International Diabetes Federation.

Maleki, S. J., Crespo, J. F., & Cabanillas, B. (2019). Anti-inflammatory effects of flavonoids. Food Chemistry, 299, 125124.

Martín, M. Á., & Ramos, S. (2021). Dietary flavonoids and insulin signaling in diabetes and obesity. Cells, 10(6), 1474.

Matos, A. L., et al. (2020). The benefits of flavonoids in diabetic retinopathy. Nutrients, 12(10), 3169.

Moraes, G. V., et al. (2022). Potencial antioxidante dos flavonoides e aplicações terapêuticas. Research, Society and Development, 11(14), e238111436225–e238111436225.

Nansel, T. R., et al. (2015). Improving dietary quality in youth with type 1 diabetes: Randomized clinical trial of a family-based behavioral intervention. International Journal of Behavioral Nutrition and Physical Activity, 12(1), 1-11.

Ortiz, L. O. M., et al. (2017). Melhores práticas de enfermagem em educação em diabetes à criança hospitalizada: Uma revisão integrativa. Revista Eletrônica de Enfermagem, 19, a56.

Panche, A. N., Diwan, A. D., & Chandra, S. R. (2016). Flavonoids: An overview. Journal of Nutritional Science, 5, e47.

Pedrinho, L. R., et al. (2020). Brinquedo terapêutico para crianças com Diabetes Mellitus tipo I: Intervenções no domicílio. Escola Anna Nery, 25, e20200278.

Queiroz, M. V. O., et al. (2016). Sensibilizando a criança com diabetes para o cuidado de si: Contribuição à prática educativa. Escola Anna Nery, 20(2), 337-343.

Ramalho, E. L. R., et al. (2023). Clinical and sociodemographic factors associated with the quality of life of children and adolescents with type 1 diabetes. Revista da Escola de Enfermagem da USP, 57, e20230195.

Ribeiro, A. L. T., et al. (2021). Avaliação de tecnologia educativa para crianças com diabetes: Estudo metodológico. Escola Anna Nery, 25, e20200282.

Sangeetha, R. (2020). Independent and synergistic activity of the flavonoids of Gracilaria corticata as promising antidiabetic agents. Brazilian Journal of Pharmaceutical Sciences, 56, e18766.

Santos, N. I. P., & Fonseca, K. Z. (2024). Alimentação saudável na adolescência: Um relato de experiência. In E-book do III Simpósio de Ciência e Tecnologia de Alimentos: Compostos bioativos do bioma brasileiro: aplicações nutricionais e industriais (Anais, Diamantina, MG). UFVJM.

Seckold, R., et al. (2019). Dietary intake and eating patterns of young children with type 1 diabetes achieving glycemic targets. BMJ Open Diabetes Research and Care, 7(1), e000663.

Silva, S. U., et al. (2018). As ações de educação alimentar e nutricional e o nutricionista no âmbito do Programa Nacional de Alimentação Escolar. Ciência & Saúde Coletiva, 23, 2671–2681.

Sociedade Brasileira de Diabetes. (2022). Diretriz da Sociedade Brasileira de Diabetes. AC Farmacêutica.

Wang, T., Li, Q., & Bi, K. (2018). Bioactive flavonoids in medicinal plants: Structure, activity and biological fate. Asian Journal of Pharmaceutical Sciences, 13(1), 12–23.

Published

28-12-2025

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Article

How to Cite

Ingrid dos Prazeres Santos, N., & Zanoti Fonseca, K. (2025). Food and nutritional education: benefits of flavonoid consumption by children with Diabetes Mellitus. Cadernos De Educação Tecnologia E Sociedade, 18(4), 1375-1386. https://doi.org/10.14571/brajets.v18.n4.1375-1386